Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089549 | 1.00 | ADRA1A (0.55) | ADRA1AADRA2AADRB2ADRA2BADRA2C | |
| SCHEMBL15631290 | 0.76 | ADRA1A (0.54) | ADRA1AADRA2AADRB2ADRA2BADRA2C | |
| SCHEMBL22460317 | 0.75 | ADRA2A (0.50) | ADRA1AADRA2AADRB2ADRA2BADRA2C | |
| SCHEMBL1691820 | 0.71 | ADRA2A (1.00) | ADRA1AADRA2AADRB2ADRA2BADRA2C | |
| SCHEMBL13158583 | 0.71 | ADRA2A (1.00) | ADRA1AADRA2AADRB2ADRA2BADRA2C | |
| SCHEMBL14137929 | 0.69 | KDM4E (0.60) | ADRA1AADRA2AADRB2ADRA2CHSD17B10 | |
| SCHEMBL16216157 | 0.69 | ADRA2A (0.68) | ADRA1AADRA2AADRB2ADRA2BADRA2C | |
| SCHEMBL9095132 | 0.69 | ADRA2A (0.58) | ADRA1AADRA2AADRB2ADRA2BADRA2C | |
| SCHEMBL19360100 | 0.69 | KDM4E (0.70) | ADRA1AADRA2AADRA2BADRA2CHSD17B10 | |
| SCHEMBL9095138 | 0.69 | ADRA2A (0.58) | ADRA1AADRA2AADRB2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527830-A | Drugs for the treatment of cardiac arrest and other shock states | THE OHIO STATE UNIVERSITY (US) | 1996-06-18 | — | — | US | claimed |
| US-5527830-A | Drugs for the treatment of cardiac arrest and other shock states | THE OHIO STATE UNIVERSITY (US) | 1996-06-18 | — | — | US | disclosed |