Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445611 | 0.84 | RAB9A (0.49) | RAB9ANPC1POLBALDH1A1HPGD | |
| SCHEMBL22461002 | 0.84 | RAB9A (0.49) | RAB9ANPC1POLBALDH1A1HPGD | |
| SCHEMBL22445612 | 0.84 | RAB9A (0.49) | RAB9ANPC1POLBALDH1A1HPGD | |
| SCHEMBL903372 | 0.76 | RAB9A (0.41) | RAB9AALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8349679 | 0.76 | RAB9A (0.41) | RAB9AALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL2720009 | 0.72 | TRPM8 (0.69) | NPC1ALDH1A1L3MBTL1HTT | |
| SCHEMBL2720006 | 0.72 | TRPM8 (0.69) | NPC1ALDH1A1L3MBTL1HTT | |
| SCHEMBL26539118 | 0.72 | ALDH1A1 (0.43) | RAB9APOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3814687 | 0.71 | POLB (0.40) | RAB9ANPC1POLBALDH1A1HPGD | |
| SCHEMBL8859640 | 0.70 | ALDH1A1 (0.45) | RAB9ANPC1POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191151-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | ONCOVALENT THERAPEUTICS INC. (US) | 2020-09-24 | — | — | WO | disclosed |