Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31653994 | 0.80 | KCNA5 (0.48) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL10153606 | 0.80 | KCNA5 (0.48) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL11122542 | 0.79 | HDAC4 (0.68) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL4532733 | 0.76 | HDAC4 (1.00) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL3704673 | 0.76 | HDAC6 (0.63) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL409869 | 0.75 | ALDH1A1 (0.66) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL27614723 | 0.75 | HDAC4 (0.68) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL24004621 | 0.74 | POLB (0.46) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL13958960 | 0.74 | GLS (0.49) | HDAC4HDAC7HDAC5HDAC3HDAC8 | |
| SCHEMBL9667100 | 0.73 | MEN1 (0.43) | HDAC4HDAC7HDAC5HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | ANXA6, ANXA1, ANXA11 | HDAC4 1593/4885HDAC7 1607/4885HDAC5 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.