SCHEMBL22462397

SCHEMBL22462397

CC(C)CC1CCCC(NC(=O)c2cc(C(N)=O)cc(C(N)=O)c2)C1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
GRM5 P41594 7/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.37
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
IRAK4 Q9NWZ3 1/20 0.37
CTSD P07339 2/20 0.37
BACE1 P56817 2/20 0.37
MAPT P10636 1/20 0.36
PTGES O14684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2450437 0.94 GRM5 (0.45) CYP2D6CYP2C9GRM5MEN1KMT2A
SCHEMBL22462454 0.85 TSHR (0.43) CYP2C9GRM5MEN1KMT2ATSHR
SCHEMBL22462415 0.84 SMYD3 (0.43) CYP2C9MEN1KMT2ANPC1RAB9A
SCHEMBL22462388 0.82 TSHR (0.42) GRM5MEN1KMT2ATSHRCA12
SCHEMBL22462386 0.82 GRM5 (0.44) CYP2D6CYP2C9GRM5MEN1KMT2A
SCHEMBL22462380 0.80 GRM5 (0.40) CYP2D6CYP2C9GRM5MEN1KMT2A
SCHEMBL2452863 0.78 GRM5 (0.48) GRM5MEN1KMT2ATSHRCA12
SCHEMBL2452310 0.77 TSHR (0.47) GRM5MEN1KMT2ATSHRCA12
SCHEMBL2452172 0.77 SMYD3 (0.44) CYP2C9MEN1KMT2ANPC1HPGD
SCHEMBL16138558 0.75 ALDH1A1 (0.45) KMT2ACA12CA9HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200384678-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2020-12-10 US disclosed
EP-3715092-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2020-09-30 EP disclosed