SCHEMBL2452172

SCHEMBL2452172

CC(C)CC1CCC(NC(=O)c2cc(C(=O)NC3CCC(CC(C)C)CC3)cc(C(=O)NC3CCC(CC(C)C)CC3)c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 4/20 0.44
MAPK14 Q16539 6/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
BRD4 O60885 3/20 0.43
CYP2C9 P11712 2/20 0.43
HSPB1 P04792 1/20 0.43
MAPK11 Q15759 1/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
GRN P28799 1/20 0.41
SORT1 Q99523 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22462415 0.93 SMYD3 (0.43) SMYD3MAPK14KMT2AMEN1BRD4
SCHEMBL24449757 0.86 MEN1 (0.56) SMYD3KMT2AMEN1BRD4NPC1
SCHEMBL2450437 0.82 GRM5 (0.45) KMT2AMEN1CYP2C9NPC1RAB9A
SCHEMBL2454233 0.81 SMYD3 (0.48) SMYD3MAPK14KMT2AMEN1CYP2C9
SCHEMBL2909582 0.80 RAB9A (0.57) SMYD3KMT2AMEN1NPC1RAB9A
SCHEMBL2452125 0.79 NPC1 (0.60) SMYD3KMT2AMEN1BRD4NPC1
SCHEMBL2450391 0.79 ALDH1A1 (0.49) SMYD3MAPK14KMT2AMEN1CYP2C9
SCHEMBL2452468 0.78 NPC1 (0.48) SMYD3KMT2AMEN1BRD4NPC1
SCHEMBL9979175 0.78 TRPV1 (0.38) SMYD3MAPK14KMT2ABRD4CYP2C9
SCHEMBL9979263 0.78 TAS1R3 (0.46) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115556446-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
CN-115556441-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
US-20200384678-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2020-12-10 US disclosed
EP-3715092-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2020-09-30 EP disclosed
EP-2096137-B1 NOVEL POLYOLEFIN RESIN COMPOSITION AND MOLDED RESIN OBTAINED THEREFROM NEW JAPAN CHEM CO LTD (JP) 2011-09-14 EP disclosed
US-20100016491-A1 NOVEL POLYOLEFIN RESIN COMPOSITION AND MOLDED RESIN OBTAINED THEREFROM NEW JAPAN CHEMICAL CO., LTD. (JP) 2010-01-21 US disclosed
EP-2096137-A1 NOVEL POLYOLEFIN RESIN COMPOSITION AND MOLDED RESIN OBTAINED THEREFROM New Japan Chemical Co., Ltd. (JP) 2009-09-02 EP disclosed