SCHEMBL224652

SCHEMBL224652

OB(O)c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
HPGD P15428 5/20 0.54
HSD17B10 Q99714 4/20 0.54
CYP3A4 P08684 2/20 0.54
TSHR P16473 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CYP1A2 P05177 4/20 0.48
CYP1A1 P04798 1/20 0.48
CYP1B1 Q16678 1/20 0.48
KDM4E B2RXH2 5/20 0.46
MAPT P10636 1/20 0.46
ERBB2 P04626 1/20 0.45
FYN P06241 1/20 0.45
MAOA P21397 1/20 0.45
ACHE P22303 1/20 0.45
AHR P35869 1/20 0.45
THRB P10828 1/20 0.44
KMT2A Q03164 4/20 0.40
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29840683 1.00 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL2597530 0.91 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL19766248 0.88 HPGD (0.59) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL29951892 0.85 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL13080593 0.85 CYP1A2 (0.53) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL12431962 0.85 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL28486608 0.82 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL11991170 0.82 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL1816278 0.81 CYP1A2 (0.65) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL19939964 0.81 HPGD (0.37) ALDH1A1HPGDHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 936 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250258130-A1 POLAR FLUID GATED FIELD EFFECT DEVICES GRAPHWEAR TECHNOLOGIES INC. 2025-08-14 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
WO-2025099017-A1 PH SENSOR, METHOD FOR PRODUCING SUCH A SENSOR, AND METHOD FOR MEASURING PH USING SUCH A SENSOR GRAPHEAL (FR) 2025-05-15 WO claimed
US-12298215-B2 Polar fluid gated field effect devices GRAPHWEAR TECHNOLOGIES INC. (US) 2025-05-13 US claimed
CN-119615641-A Method for preparing long-afterglow multicolor phosphorescent textile by adopting arylboronic acid derivative 山东中康国创先进印染技术研究院有限公司 2025-03-14 CN claimed
CN-119563107-A Device, and apparatus and method for measuring hydroxide ion concentration using same 三井金属矿业株式会社 2025-03-04 CN claimed
CN-119504771-A Spiropyran derivative with color and fluorescence dual switch, photochromic material, and preparation method and application thereof 安徽省东超科技有限公司 2025-02-25 CN claimed
CN-119100976-A Aggregation-induced luminescent charge type free radical photosensitizer and preparation method and antibacterial application thereof 南昌航空大学 2024-12-10 CN claimed
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 CN claimed
EP-2739977-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS Massachusetts Institute of Technology (US) 2014-06-11 EP claimed
US-20130183249-A1 Stimulus Sensitive Magnetic Nanocomposite Using Pyrene Polymer, and Contrast Medium Composition Containing the Nanocomposite INDUSTRY ACADEMIC COOPERATION FOUNDATION YOUNSEI UNIVERSITY (KR) 2013-07-18 US claimed
US-20130035567-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS NATIONAL SCIENCE FOUNDATION 2013-02-07 US claimed
WO-2013019722-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
US-8361484-B2 Polymer systems for lung volume reduction therapy AERIS THERAPEUTICS, INC. (US) 2013-01-29 US claimed
US-20120282705-A1 Explosives Detection Substrate and Methods of Using the Same UNIVERSITY OF CONNECTICUT (US) 2012-11-08 US claimed
WO-2011053247-A1 METHOD FOR THE DETECTION OF AN ANALYTE BY SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-05-05 WO claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy GFER, MUC1, CTH ALDH1A1 1749/4885HPGD 38/4885HSD17B10 323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.