Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | PTAFR | P25105 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GMNN | O75496 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704033 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| Vb-201 SCHEMBL2071230 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL2231559 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL704034 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL2232633 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL2232585 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| Vb-201 SCHEMBL14322398 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| Vb-201 SCHEMBL2071110 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL20143296 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL703690 | 0.85 | RECQL (0.81) | RECQLADRA1DPTAFRHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195937-A1 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-08-11 | — | — | US | claimed |
| US-8999960-B2 | Oxidized thiophospholipid compounds and uses thereof | VASCULAR BIOGENICS LTD. (IL) | 2015-04-07 | — | — | US | disclosed |
| US-20110195937-A1 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-08-11 | — | — | US | disclosed |
| EP-2348864-A2 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010041242-A2 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195937-A1 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | PRDX2, PRDX1, LPO | RECQL 1572/4885ADRA1D 2031/4885PTAFR 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.