Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442421 | 0.73 | KDM4C (0.46) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL17694181 | 0.72 | KDM4C (0.40) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL2804255 | 0.70 | KDM4C (0.40) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL29897994 | 0.69 | HCAR2 (0.44) | PPARA | |
| SCHEMBL630634 | 0.68 | HDAC6 (0.41) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL6421810 | 0.67 | RAB9A (0.49) | — | |
| SCHEMBL30295641 | 0.67 | RAB9A (0.49) | — | |
| SCHEMBL30207 | 0.67 | PPARA (0.46) | KMOPPARA | |
| SCHEMBL23416935 | 0.67 | KDM4C (0.38) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL11162689 | 0.67 | KDM4C (0.38) | KDM4CHDAC1HDAC6CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023231795-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | 北京八亿时空液晶科技股份有限公司 | 2023-12-07 | — | — | WO | claimed |
| WO-2021083167-A1 | SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-05-06 | — | — | WO | disclosed |
| WO-2020224656-A1 | BISHETEROCYCLIC CARBONYL SUBSTITUTED DIHYDROPYRAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2020-11-12 | — | — | WO | disclosed |
| WO-2020192562-A1 | SUBSTITUTED HETEROCYCLIC AMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2020-10-01 | — | — | WO | disclosed |