SCHEMBL22470752

SCHEMBL22470752

Cn1cc2c(c1)CNC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1528505 0.83 PNMT (0.46)
SCHEMBL15290383 0.67
SCHEMBL15856670 0.67 MAOA (0.39)
SCHEMBL256365 0.67 TSHR (0.38)
SCHEMBL1393717 0.65
Hydrochloric Acid SCHEMBL2750120 0.64 SOD3 (0.34)
SCHEMBL11768224 0.63 PNMT (0.39)
SCHEMBL28181453 0.63
SCHEMBL4701951 0.62
Hydrochloric Acid SCHEMBL28869408 0.61 PNMT (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595267-B2 Preparation method for amide compound and application thereof in field of medicine SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD. (CN) 2026-04-07 US disclosed
CN-113631541-B Preparation method of amide compound and application of amide compound in medicine field 上海华汇拓医药科技有限公司 2024-10-01 CN disclosed
US-20220098178-A1 Preparation Method for Amide Compound and Application Thereof in Field of Medicine ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) 2022-03-31 US disclosed
CN-113631541-A Preparation method of amide compound and application of amide compound in field of medicine 上海华汇拓医药科技有限公司 2021-11-09 CN disclosed
WO-2020192650-A1 PREPARATION METHOD FOR AMIDE COMPOUND AND APPLICATION THEREOF IN FIELD OF MEDICINE 上海华汇拓医药科技有限公司 2020-10-01 WO disclosed