Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 4/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | PDE4A | P27815 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730548 | 0.91 | ADORA2B (0.77) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL22471386 | 0.91 | TNF (0.70) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL22471491 | 0.86 | ADORA2B (0.82) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL8570022 | 0.86 | ADORA2B (0.77) | TNFADORA2BCYP1A2PDE4APMP22 | |
| Bisdionin B SCHEMBL29896692 | 0.84 | ADORA2B (0.74) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL315740 | 0.83 | ADORA2B (0.82) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL10519761 | 0.83 | ADORA2B (0.71) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL25668861 | 0.82 | ADORA2B (0.76) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL9123779 | 0.82 | ADORA2B (0.79) | TNFADORA2BCYP1A2PDE4APMP22 | |
| SCHEMBL7384282 | 0.81 | ADORA2B (0.69) | TNFADORA2BCYP1A2PDE4APMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912598-B | Nucleoside derivative for preventing and treating inflammatory reaction and application thereof | 四川大学华西医院 | 2022-09-13 | — | — | CN | disclosed |
| WO-2020192665-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | 四川大学华西医院 | 2020-10-01 | — | — | WO | disclosed |