SCHEMBL315740

SCHEMBL315740

CCCn1c(=O)c2c(ncn2C)n(C)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA2B P29275 9/20 0.82
▸ ADORA2A P29274 5/20 0.82
▸ PDE4A P27815 5/20 0.82
▸ PDE4B Q07343 5/20 0.82
▸ PDE4C Q08493 5/20 0.82
▸ PDE4D Q08499 5/20 0.82
▸ BLM P54132 2/20 0.82
▸ CYP1A2 P05177 2/20 0.82
▸ PMP22 Q01453 2/20 0.82
▸ CYP3A4 P08684 1/20 0.82
▸ HSD17B10 Q99714 1/20 0.82
▸ GLA P06280 1/20 0.67
▸ TNF P01375 2/20 0.65
▸ ACHE P22303 2/20 0.65
▸ PIK3CD O00329 1/20 0.65
▸ POLB P06746 1/20 0.65
▸ ADORA3 P0DMS8 1/20 0.65
▸ CNR1 P21554 1/20 0.65
▸ ADORA1 P30542 1/20 0.65
▸ NTSR1 P30989 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisdionin B SCHEMBL29896692 0.92 ADORA2B (0.74) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL516018 0.91 PDE4A (0.78) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL316911 0.90 PDE4A (1.00) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL266179 0.89 PDE4A (0.72) ADORA2BADORA2APDE4APDE4BPDE4C
Bisdionin C SCHEMBL10018600 0.89 CHIT1 (0.75) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL516446 0.89 ADORA2A (0.74) ADORA2BADORA2APDE4APDE4BPDE4C
Bisdionin D SCHEMBL16120988 0.89 ADORA2B (0.79) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL23144749 0.88 PDE4A (0.70) ADORA2BADORA2APDE4APDE4BPDE4C
Pentifylline SCHEMBL147256 0.88 PDE4A (0.70) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL27334771 0.88 PDE4A (0.70) ADORA2BADORA2APDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8193201-B2 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines METAPROTEOMICS, LLC (US) 2012-06-05 — — US claimed
US-20110172253-A1 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES METAPROTEOMICS, LLC (US) 2011-07-14 — — US claimed
EP-2338481-A2 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines Metaproteomics, LLC (US) 2011-06-29 — — EP claimed
US-7914831-B2 Alpha acids, isoalpha acids, reduced isoalpha acids, tetra-hydroisoalpha acids, hexa-hydroisoalpha acids, beta acids from hops; nontoxic METAPROTEOMICS, LLC (US) 2011-03-29 — — US claimed
US-20070185213-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2007-08-09 — — US claimed
EP-1718312-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES Metaproteomics, LLC (US) 2006-11-08 — — EP claimed
WO-2005084230-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES METAPROTEOMICS, LLC (US) 2005-09-15 — — WO claimed
US-20050191375-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2005-09-01 — — US claimed
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2026-04-30 — — US disclosed
US-20250320430-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-10-16 — — US disclosed
WO-2025134877-A1 KIT AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2025-06-26 — — WO disclosed
US-20250129308-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-04-24 — — US disclosed
CN-119404296-A Semiconductor processing liquid, method for processing object to be processed, and method for manufacturing electronic device 富士胶片株式会社 2025-02-07 — — CN disclosed
US-20250017209-A1 COMPOSITION, MANUFACTURING METHOD FOR SEMICONDUCTOR ELEMENT, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE FUJIFILM CORPORATION (JP) 2025-01-16 — — US disclosed
WO-2008137318-A1 COMPOSITIONS AND METHODS FOR TREATING DISORDERS ASSOCIATED WITH SALT OR FLUID RETENTION IRONWOOD PHARMACEUTICALS, INC. (US) 2008-11-13 — — WO disclosed
US-20070185213-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2007-08-09 — — US disclosed
EP-1718312-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES Metaproteomics, LLC (US) 2006-11-08 — — EP disclosed
WO-2005084230-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES METAPROTEOMICS, LLC (US) 2005-09-15 — — WO disclosed
US-20050191375-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2005-09-01 — — US disclosed
US-20050096282-A1 Adeno-associated virus-delivered ribozyme compositions and methods for the treatment of retinal diseases FLORIDA RESEARCH FOUNDATION, UNIVERSITY OF 2005-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185213-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines HMOX1, HMOX2, HPGDS ADORA2B 1339/4885ADORA2A 608/4885PDE4A 772/4885
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE TPMT, P2RY13, TST ADORA2B 689/4885ADORA2A 559/4885PDE4A 3690/4885
US-20110172253-A1 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES HMOX1, HMOX2, HPGDS ADORA2B 1339/4885ADORA2A 608/4885PDE4A 772/4885
US-20250017209-A1 COMPOSITION, MANUFACTURING METHOD FOR SEMICONDUCTOR ELEMENT, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE SPOUT1, SRM, SMOX ADORA2B 3037/4885ADORA2A 2668/4885PDE4A 1888/4885
US-20050191375-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines HMOX1, HMOX2, HPGDS ADORA2B 1339/4885ADORA2A 608/4885PDE4A 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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