SCHEMBL315740

SCHEMBL315740

CCCn1c(=O)c2c(ncn2C)n(C)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 9/20 0.82
ADORA2A P29274 5/20 0.82
PDE4A P27815 5/20 0.82
PDE4B Q07343 5/20 0.82
PDE4C Q08493 5/20 0.82
PDE4D Q08499 5/20 0.82
BLM P54132 2/20 0.82
CYP1A2 P05177 2/20 0.82
PMP22 Q01453 2/20 0.82
CYP3A4 P08684 1/20 0.82
HSD17B10 Q99714 1/20 0.82
GLA P06280 1/20 0.67
TNF P01375 2/20 0.65
ACHE P22303 2/20 0.65
PIK3CD O00329 1/20 0.65
POLB P06746 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
CNR1 P21554 1/20 0.65
ADORA1 P30542 1/20 0.65
NTSR1 P30989 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisdionin B SCHEMBL29896692 0.92 ADORA2B (0.74) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL516018 0.91 PDE4A (0.78) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL316911 0.90 PDE4A (1.00) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL266179 0.89 PDE4A (0.72) ADORA2BADORA2APDE4APDE4BPDE4C
Bisdionin D SCHEMBL16120988 0.89 ADORA2B (0.79) ADORA2BADORA2APDE4APDE4BPDE4C
Bisdionin C SCHEMBL10018600 0.89 CHIT1 (0.75) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL516446 0.89 ADORA2A (0.74) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL23144749 0.88 PDE4A (0.70) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL27334771 0.88 PDE4A (0.70) ADORA2BADORA2APDE4APDE4BPDE4C
Pentifylline SCHEMBL147256 0.88 PDE4A (0.70) ADORA2BADORA2APDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8193201-B2 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines METAPROTEOMICS, LLC (US) 2012-06-05 US claimed
US-20110172253-A1 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES METAPROTEOMICS, LLC (US) 2011-07-14 US claimed
EP-2338481-A2 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines Metaproteomics, LLC (US) 2011-06-29 EP claimed
US-7914831-B2 Alpha acids, isoalpha acids, reduced isoalpha acids, tetra-hydroisoalpha acids, hexa-hydroisoalpha acids, beta acids from hops; nontoxic METAPROTEOMICS, LLC (US) 2011-03-29 US claimed
US-20070185213-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2007-08-09 US claimed
EP-1718312-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES Metaproteomics, LLC (US) 2006-11-08 EP claimed
WO-2005084230-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES METAPROTEOMICS, LLC (US) 2005-09-15 WO claimed
US-20050191375-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2005-09-01 US claimed
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2026-04-30 US disclosed
US-20250320430-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-10-16 US disclosed
WO-2025134877-A1 KIT AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2025-06-26 WO disclosed
US-20250129308-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-04-24 US disclosed
CN-119404296-A Semiconductor processing liquid, method for processing object to be processed, and method for manufacturing electronic device 富士胶片株式会社 2025-02-07 CN disclosed
US-20250017209-A1 COMPOSITION, MANUFACTURING METHOD FOR SEMICONDUCTOR ELEMENT, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE FUJIFILM CORPORATION (JP) 2025-01-16 US disclosed
WO-2008137318-A1 COMPOSITIONS AND METHODS FOR TREATING DISORDERS ASSOCIATED WITH SALT OR FLUID RETENTION IRONWOOD PHARMACEUTICALS, INC. (US) 2008-11-13 WO disclosed
US-20070185213-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2007-08-09 US disclosed
EP-1718312-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES Metaproteomics, LLC (US) 2006-11-08 EP disclosed
WO-2005084230-A2 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES METAPROTEOMICS, LLC (US) 2005-09-15 WO disclosed
US-20050191375-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2005-09-01 US disclosed
US-20050096282-A1 Adeno-associated virus-delivered ribozyme compositions and methods for the treatment of retinal diseases FLORIDA RESEARCH FOUNDATION, UNIVERSITY OF 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185213-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines HMOX1, HMOX2, HPGDS ADORA2B 1339/4885ADORA2A 608/4885PDE4A 772/4885
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE TPMT, P2RY13, TST ADORA2B 689/4885ADORA2A 559/4885PDE4A 3690/4885
US-20110172253-A1 SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES HMOX1, HMOX2, HPGDS ADORA2B 1339/4885ADORA2A 608/4885PDE4A 772/4885
US-20250017209-A1 COMPOSITION, MANUFACTURING METHOD FOR SEMICONDUCTOR ELEMENT, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE SPOUT1, SRM, SMOX ADORA2B 3037/4885ADORA2A 2668/4885PDE4A 1888/4885
US-20050191375-A1 Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines HMOX1, HMOX2, HPGDS ADORA2B 1339/4885ADORA2A 608/4885PDE4A 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.