Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 4/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.65 |
| ▸ | PDE4A | P27815 | 3/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22471325 | 0.91 | TNF (0.71) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9122988 | 0.90 | ADORA2B (0.74) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL10519761 | 0.90 | ADORA2B (0.71) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL25668861 | 0.86 | ADORA2B (0.76) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9123285 | 0.85 | ADORA2B (0.74) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL8686059 | 0.85 | ADORA2B (0.74) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9123835 | 0.85 | ADORA2B (0.74) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL22471491 | 0.85 | ADORA2B (0.82) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL8570022 | 0.85 | ADORA2B (0.77) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL315740 | 0.84 | ADORA2B (0.82) | TNFADORA2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260083743-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY (CN) | 2026-03-26 | — | — | US | disclosed |
| US-20220288084-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY (CN) | 2022-09-15 | — | — | US | disclosed |
| CN-109912598-B | Nucleoside derivative for preventing and treating inflammatory reaction and application thereof | 四川大学华西医院 | 2022-09-13 | — | — | CN | disclosed |
| EP-3950689-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | West China Hospital of Sichuan University (CN) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020192665-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | 四川大学华西医院 | 2020-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083743-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | SLC5A1, PC, LDHA | TNF 51/4885ADORA2B 102/4885PDE4A 2742/4885 |
| US-20220288084-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | PNP, HMGB3, ADAR | TNF 69/4885ADORA2B 4/4885PDE4A 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.