Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747724 | 0.81 | CHRM2 (0.45) | KMT2AL3MBTL1USP14DRD2HTR2C | |
| SCHEMBL12665777 | 0.77 | CHRM2 (0.37) | CHRM2CHRM1CHRM3 | |
| SCHEMBL27033256 | 0.69 | OGA (0.31) | — | |
| SCHEMBL14454559 | 0.69 | CHRM2 (0.36) | CHRM2CHRM1CHRM3 | |
| SCHEMBL22307599 | 0.69 | CHRM2 (0.36) | CHRM2CHRM1CHRM3 | |
| SCHEMBL19814985 | 0.67 | GRM2 (0.40) | HPGDALDH1A1LMNACYP2C19HSD17B10 | |
| SCHEMBL27558014 | 0.67 | ALDH1A1 (0.40) | KMT2AUSP14ALDH1A1CHRM2CHRM1 | |
| SCHEMBL18716616 | 0.67 | ALDH1A1 (0.40) | KMT2AUSP14ALDH1A1CHRM2CHRM1 | |
| SCHEMBL499877 | 0.67 | HTR2A (0.40) | DRD2HTR2CALDH1A1 | |
| SCHEMBL28395810 | 0.66 | LMNA (0.43) | KMT2AL3MBTL1HPGDALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020192581-A1 | WEE1 INHIBITOR AND PREPARATION AND USE THEREOF | 首药控股(北京)有限公司 | 2020-10-01 | — | — | WO | disclosed |