Acetamide

Acetamide

SCHEMBL22471750

CC(N)=O.O=S(=O)(O)Oc1ccc(O)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CISD1 Q9NZ45 1/20 0.49
STS P08842 3/20 0.46
PARP10 Q53GL7 1/20 0.44
GAA P10253 2/20 0.43
PKM P14618 1/20 0.43
CA2 P00918 5/20 0.42
CA9 Q16790 5/20 0.42
CA1 P00915 4/20 0.42
ELANE P08246 1/20 0.41
GLA P06280 1/20 0.40
LMNA P02545 1/20 0.39
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232089 0.88 CISD1 (0.58) CISD1GAAPKMCA2CA9
Potassium SCHEMBL565329 0.86 CISD1 (0.56) CISD1GAAPKMCA2CA9
Lithium SCHEMBL17969202 0.86 CISD1 (0.56) CISD1GAAPKMCA2CA9
Formaldehyde SCHEMBL7924386 0.84 CISD1 (0.55) CISD1GAAPKMCA2CA9
Urea SCHEMBL27973636 0.83 CA2 (0.50) CISD1STSPARP10GAACA2
Glycine SCHEMBL9110024 0.81 CISD1 (0.46) CISD1STSPARP10GAAPKM
Benzoquinone SCHEMBL11308710 0.80 CISD1 (0.51) CISD1GAAPKMCA2CA9
SCHEMBL8007759 0.78 PKM (0.63) CISD1GAAPKMCA2CA9
SCHEMBL7910581 0.78 GLA (0.53) CISD1STSGAACA2CA9
SCHEMBL11383141 0.78 ALDH1A1 (0.69) CISD1GAAPKMCA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020194563-A1 AGENT FOR PREVENTING OR IMPROVING SYMPTOMS OR DISEASE CAUSED BY PHENOLS 国立大学法人東北大学 2020-10-01 WO disclosed