Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472890 | 0.99 | MAPK1 (0.41) | MAPK1CHRM1MEN1KMT2AAOC3 | |
| SCHEMBL22472880 | 0.88 | MMP13 (0.35) | MAPK1KMT2AAOC3ALDH1A1 | |
| SCHEMBL22472924 | 0.87 | MMP13 (0.36) | MAPK1KMT2AAOC3ALDH1A1 | |
| SCHEMBL21597934 | 0.86 | MAPK1 (0.41) | MAPK1CHRM1MEN1KMT2AAKR1C3 | |
| SCHEMBL22449299 | 0.84 | MAPK1 (0.39) | MAPK1CHRM1MEN1KMT2AAOC3 | |
| SCHEMBL22472905 | 0.76 | ALDH1A1 (0.53) | MAPK1CHRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL16992357 | 0.75 | CHRM4 (0.51) | MAPK1CHRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL4516164 | 0.75 | L3MBTL1 (0.52) | MAPK1CHRM1ALDH1A1 | |
| SCHEMBL22449321 | 0.74 | MMP13 (0.34) | MAPK1KMT2AAOC3ALDH1A1 | |
| SCHEMBL12568160 | 0.73 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | MAPK1 1738/4885CHRM1 1/4885MEN1 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.