Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GOT1 | P17174 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Pentanol SCHEMBL28251154 | 0.82 | EGFR (0.42) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL30827215 | 0.81 | NPC1 (0.44) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL6008542 | 0.80 | NPC1 (0.47) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL5436460 | 0.80 | NPC1 (0.47) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL291352 | 0.80 | NPC1 (0.47) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL30662856 | 0.77 | ERN1 (0.45) | LMNAKDM4EALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8152019 | 0.77 | NPC1 (0.44) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL7547757 | 0.77 | NPC1 (0.44) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL27603097 | 0.76 | PLAU (0.36) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL29982208 | 0.75 | S100A4 (0.41) | NPC1RAB9ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563080-A | Preparation method of olaparib | 台湾神隆股份有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-109415345-A | Broad spectrum influenza inhibitor based on pyridazinone | 豪夫迈·罗氏有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-108164468-A | A kind of PARP inhibitor, its pharmaceutical composition, preparation method and application | 上海卫岑医药科技有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-105143215-B | Bruton's tyrosine kinase inhibitors | 豪夫迈·罗氏有限公司 | 2017-12-08 | — | — | CN | claimed |
| CN-107428762-A | Phthalazinone derivatives, preparation method and the usage | 四川科伦博泰生物医药股份有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-104662018-B | Substituted Heterobicyclic compounds, composition and its medical applications | 阿迪维纳斯治疗有限公司 | 2017-10-24 | — | — | CN | claimed |
| CN-107207504-A | Phthalazinone derivatives, preparation method and the usage | 四川科伦博泰生物医药股份有限公司 | 2017-09-26 | — | — | CN | claimed |
| CN-105073741-B | Phthalazinones and isoquinolinones as ROCK inhibitors | 百时美施贵宝公司 | 2017-08-08 | — | — | CN | claimed |
| CN-105026386-B | Antiviral compound | 弗·哈夫曼-拉罗切有限公司 | 2017-08-01 | — | — | CN | claimed |
| CN-104812746-B | Bruton's tyrosine kinase inhibitors | 弗·哈夫曼-拉罗切有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-102227409-B | Pyridine-3-carboxyamide derivative | KOWA CO | 2014-03-26 | — | — | CN | claimed |
| CN-102219903-B | Polybenzoxazole copolymer with phthalazinone terphenyl structure and preparation method thereof | UNIV DALIAN TECH | 2013-06-19 | — | — | CN | claimed |
| CN-102869258-A | Dihydropyridophthalazinone inhibitors of poly (ADP-ribose) polymerase (PARP) for the treatment of PTEN gene deficiency related diseases | BIOMARIN PHARM INC | 2013-01-09 | — | — | CN | claimed |
| CN-102180909-A | Iridium complex phosphor material taking phthalazine derivative as ligand and preparation method thereof | UNIV NANJING POSTS & TELECOMM | 2011-09-14 | — | — | CN | claimed |
| CN-102171214-A | Dihydropyridophthalazinone inhibitors of poly (ADP-ribose) polymerase (PARP) | BIOMARIN PHARM INC | 2011-08-31 | — | — | CN | claimed |
| CN-1720245-A | Oxime ester photoinitiators with heteroaryl groups | CIBA SC HOLDING AG (CH) | 2006-01-11 | — | — | CN | claimed |
| CN-1103866-A | Nes pesticides | RHONE POULENC AGRICULTURE (GB) | 1995-06-21 | — | — | CN | claimed |
| US-4367173-A | POLYVINYL CHLORIDE, POLYETHYLENE | BASF AKTIENGESELLSCHAFT (DE) | 1983-01-04 | — | — | US | claimed |
| EP-4511128-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| EP-0086438-A1 | Process and intermediates for preparing 4-hydroxymethyl-1-phthalazone derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1983-08-24 | — | — | EP | disclosed |