Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GOT1 | P17174 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291352 | 0.81 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL30827215 | 0.78 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL224748 | 0.77 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL5436460 | 0.77 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL6008542 | 0.77 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL4254162 | 0.75 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL4254166 | 0.75 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL7547757 | 0.74 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL8372463 | 0.73 | LMNA (0.47) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| 1-Pentanol SCHEMBL28251154 | 0.73 | EGFR (0.42) | NPC1RAB9ASMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066672-A | OF GIVEN FORMULA COMPRISING A SUBSTITUTED AMINOALKYL(AMIDO OR ALKYLAMINO)ALKYL(AMIDO OR ALKYLAMINO)ALKYL(ALKENE, ALKYL OR ALKOXYCARBONYL) | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-0882699-A1 | AMINO COMPOUNDS AND ANGIOTENSIN IV RECEPTOR AGONISTS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |