Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GOT1 | P17174 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547757 | 0.85 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL6008542 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL291352 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL224748 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL30827215 | 0.77 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL8152019 | 0.77 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL15715878 | 0.75 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL4254166 | 0.74 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL4254162 | 0.74 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL9114296 | 0.73 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011007835-A | OPTICAL FILM, IMAGE DISPLAY DEVICE INCLUDING THE SAME AND NEW POLYMER | NIPPON SHOKUBAI CO LTD | 2011-01-13 | — | — | JP | disclosed |
| US-7307276-B2 | Layer configuration comprising an electron-blocking element | AGFA-GEVAERT (BE) | 2007-12-11 | — | — | US | disclosed |
| US-7056600-B2 | Layer configuration comprising an electron-blocking element | AGFA GEVAERT (BE) | 2006-06-06 | — | — | US | disclosed |
| WO-2004019348-A1 | LAYER CONFIGURATION COMPRISING AN ELECTRON-BLOCKING ELEMENT | AGFA-GEVAERT (BE) | 2004-03-04 | — | — | WO | disclosed |
| US-20040040594-A1 | Layer configuration comprising an electron-blocking element | AGFA-GEVAERT (BE) | 2004-03-04 | — | — | US | disclosed |
| US-20040044214-A1 | Layer configuration comprising an electron-blocking element | AGFA-GEVAERT (BE) | 2004-03-04 | — | — | US | disclosed |
| WO-2004019346-A1 | LAYER CONFIGURATION COMPRISING AN ELECTRON-BLOCKING ELEMENT | AGFA-GEVAERT (BE) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044214-A1 | Layer configuration comprising an electron-blocking element | PCBP1, RER1, SCO2 | NPC1 2524/4885RAB9A 4337/4885SMN1; SMN2 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.