Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22417596 | 0.95 | TSHR (0.40) | TSHRPRKCA | |
| SCHEMBL15894729 | 0.89 | TSHR (0.44) | TSHRPRKCATHRBALDH1A1 | |
| SCHEMBL14729534 | 0.86 | TSHR (0.37) | TSHRPRKCAALDH1A1 | |
| SCHEMBL11920346 | 0.85 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL18269754 | 0.85 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL18269755 | 0.85 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL12793095 | 0.85 | TSHR (0.46) | TSHRPRKCATHRBALDH1A1 | |
| SCHEMBL14729529 | 0.85 | TSHR (0.36) | TSHRPRKCA | |
| SCHEMBL11920353 | 0.85 | AR (0.41) | PRKCATHRB | |
| SCHEMBL11920355 | 0.84 | TSHR (0.35) | TSHRPRKCATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675422-B1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | 3M INNOVATIVE PROPERTIES CO (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-2965742-B1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | 3M INNOVATIVE PROPERTIES CO (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-2675783-B1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-04-22 | — | — | EP | disclosed |
| US-10370322-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-08-06 | — | — | US | disclosed |
| EP-3502092-A1 | ADDITION-FRAGMENTATION AGENTS | 3M Innovative Properties Company (US) | 2019-06-26 | — | — | EP | disclosed |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-9403966-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-08-02 | — | — | US | disclosed |
| US-9403966-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-08-02 | — | — | US | disclosed |
| US-9320685-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-04-26 | — | — | US | disclosed |
| US-9320685-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-04-26 | — | — | US | disclosed |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-20150203658-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-07-23 | — | — | US | disclosed |
| US-20150203658-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-07-23 | — | — | US | disclosed |
| US-9056043-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-9056043-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| WO-2012112304-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-08-23 | — | — | WO | disclosed |
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-08-16 | — | — | US | disclosed |
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370322-B2 | Addition-fragmentation agents | NR4A1, PARP14, MTX1 | TSHR 1778/4885PRKCA 4445/4885THRB 2735/4885 |
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | NR4A1, PARP14, MTX1 | TSHR 1778/4885PRKCA 4445/4885THRB 2735/4885 |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | NR4A1, PARP14, MTX1 | TSHR 1778/4885PRKCA 4445/4885THRB 2735/4885 |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | NR4A1, RXRG, RXRA | TSHR 3478/4885PRKCA 3011/4885THRB 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.