SCHEMBL22476343

SCHEMBL22476343

c1ccc2c(c1)ccc1oc3cncnc3c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.43
TDP1 Q9NUW8 3/20 0.40
CYP1A2 P05177 3/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ABCG2 Q9UNQ0 2/20 0.38
PAX8 Q06710 2/20 0.38
EGFR P00533 1/20 0.38
CYP1A1 P04798 1/20 0.38
FYN P06241 1/20 0.38
MAPK3 P27361 1/20 0.38
LIMK1 P53667 1/20 0.37
HNF4A P41235 1/20 0.37
XRCC6 P12956 1/20 0.36
XRCC5 P13010 1/20 0.36
PRKDC P78527 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30075707 1.00 AHR (0.43) AHRTDP1CYP1A2NPC1RAB9A
SCHEMBL19758265 0.81 SMN1; SMN2 (0.45) TDP1CYP1A2NPC1RAB9ACYP2C9
SCHEMBL30356598 0.79 CYP1A2 (0.42) TDP1CYP1A2NPC1RAB9ACYP2C9
SCHEMBL22483141 0.79 CYP1A2 (0.42) TDP1CYP1A2NPC1RAB9ACYP2C9
SCHEMBL483929 0.78 SMN1; SMN2 (0.51) TDP1CYP1A2NPC1RAB9ACYP2C9
SCHEMBL25461393 0.77 KDM4E (0.39) CYP1A2NPC1RAB9ACYP2C19L3MBTL1
SCHEMBL22483138 0.75 EGFR (0.39) CYP1A2NPC1RAB9ACYP2C9CYP2C19
SCHEMBL26771405 0.75 SMN1; SMN2 (0.42) TDP1CYP1A2NPC1RAB9ACYP2C9
SCHEMBL22788545 0.75 CCR1 (0.44) AHRTDP1CYP1A2NPC1RAB9A
SCHEMBL30365643 0.75 CCR1 (0.44) AHRTDP1CYP1A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
WO-2023096225-A1 HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER, COMPRISING SAME 엘티소재주식회사 2023-06-01 WO disclosed
EP-3715437-B1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-01 EP disclosed
US-20210009616-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD (KR) 2021-01-14 US disclosed
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-01 US disclosed
EP-3715437-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2020-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, LEF1 AHR 437/4885TDP1 2406/4885CYP1A2 47/4885
US-20210009616-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SLC39A14, ORC3, TIMM13 AHR 1365/4885TDP1 4182/4885CYP1A2 2109/4885
US-11760769-B2 Composition and organic light-emitting device including the same CRY1, CRY2, LEF1 AHR 437/4885TDP1 2406/4885CYP1A2 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.