Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734908 | 0.89 | POLB (0.49) | GAAACEALDH1A1HSD17B10 | |
| SCHEMBL22810961 | 0.89 | POLB (0.49) | GAAACEALDH1A1HSD17B10 | |
| SCHEMBL15313443 | 0.89 | POLB (0.49) | GAAACEALDH1A1HSD17B10 | |
| SCHEMBL9892967 | 0.89 | POLB (0.49) | GAAACEALDH1A1HSD17B10 | |
| SCHEMBL21699252 | 0.89 | POLB (0.49) | GAAACEALDH1A1HSD17B10 | |
| SCHEMBL19647312 | 0.89 | GAA (0.54) | GAAKDM4EL3MBTL1ALDH1A1THRB | |
| SCHEMBL18912329 | 0.89 | GAA (0.54) | GAAKDM4EL3MBTL1ALDH1A1THRB | |
| SCHEMBL20750962 | 0.86 | GAA (0.41) | GAAACEKDM4EL3MBTL1OPRM1 | |
| SCHEMBL22600820 | 0.85 | NPC1 (0.44) | GAAACE | |
| SCHEMBL26765974 | 0.85 | NPC1 (0.44) | GAAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303366-B1 | DERIVATIVES OF DOLASTATIN 10 AND USES THEREOF | NEWBIO THERAPEUTICS INC (CN) | 2020-09-30 | — | — | EP | disclosed |