Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19443278 | 0.89 | MMP1 (0.44) | ACEMMP2MMP1FCER2GAA | |
| SCHEMBL22476544 | 0.89 | MMP1 (0.44) | ACEMMP2MMP1FCER2 | |
| SCHEMBL22476478 | 0.89 | CAPN1 (0.42) | L3MBTL1ACEAKT1MMP1FCER2 | |
| SCHEMBL23154537 | 0.89 | ACE (0.46) | POLBACEGAAALDH1A1THRB | |
| SCHEMBL25949990 | 0.89 | ACE (0.46) | POLBACEGAAALDH1A1THRB | |
| SCHEMBL18688556 | 0.89 | ACE (0.46) | POLBACEGAAALDH1A1THRB | |
| SCHEMBL22476506 | 0.89 | ACE (0.41) | L3MBTL1ACEATMGAAALDH1A1 | |
| SCHEMBL21699268 | 0.88 | CYP2C9 (0.49) | L3MBTL1POLBATMGAAALDH1A1 | |
| SCHEMBL21699258 | 0.88 | CYP2C9 (0.49) | L3MBTL1POLBATMGAAALDH1A1 | |
| SCHEMBL18683750 | 0.85 | NPC1 (0.41) | L3MBTL1ATMGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303366-B1 | DERIVATIVES OF DOLASTATIN 10 AND USES THEREOF | NEWBIO THERAPEUTICS INC (CN) | 2020-09-30 | — | — | EP | disclosed |