Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.42 |
| ▸ | TACR2 | P21452 | 5/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | CPA2 | P48052 | 1/20 | 0.35 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22476529 | 0.89 | L3MBTL1 (0.45) | TACR2ACEL3MBTL1AKT1MMP1 | |
| SCHEMBL22476544 | 0.86 | MMP1 (0.44) | ACEMMP1FCER2 | |
| SCHEMBL19443278 | 0.86 | MMP1 (0.44) | ACEMMP1FCER2 | |
| SCHEMBL23154537 | 0.86 | ACE (0.46) | ACECPA1 | |
| SCHEMBL18688556 | 0.86 | ACE (0.46) | ACECPA1 | |
| SCHEMBL25949990 | 0.86 | ACE (0.46) | ACECPA1 | |
| SCHEMBL22476555 | 0.85 | TACR2 (0.40) | CAPN1TACR2ACE | |
| SCHEMBL22476506 | 0.85 | ACE (0.41) | ACEL3MBTL1 | |
| SCHEMBL21699268 | 0.85 | CYP2C9 (0.49) | L3MBTL1 | |
| SCHEMBL21699258 | 0.85 | CYP2C9 (0.49) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303366-B1 | DERIVATIVES OF DOLASTATIN 10 AND USES THEREOF | NEWBIO THERAPEUTICS INC (CN) | 2020-09-30 | — | — | EP | disclosed |