SCHEMBL224788

SCHEMBL224788

CCCCC(=O)Oc1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.52
LMNA P02545 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
HTT P42858 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
TSHR P16473 1/20 0.51
CYP2C19 P33261 1/20 0.51
PDE4D Q08499 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
BCL9 O00512 1/20 0.49
CTNNB1 P35222 1/20 0.49
MEN1 O00255 2/20 0.47
RECQL P46063 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513733 0.95 KMT2A (0.57) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL27709110 0.93 KMT2A (0.59) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL16586533 0.93 KMT2A (0.59) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL299704 0.93 KMT2A (0.59) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL11650732 0.93 KMT2A (0.59) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL5822065 0.91 KMT2A (0.61) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL612295 0.89 BCL9 (0.60) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL6866899 0.89 KMT2A (0.61) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL6869289 0.89 KMT2A (0.56) KMT2ALMNAALDH1A1MAPTHTT
Hydrochloric Acid SCHEMBL27429774 0.87 BCL9 (0.58) KMT2ALMNAALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103495340-B The method of SOx in compound alcamines solution removal gas BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO.,LTD. (CN) 2015-11-18 CN claimed
CN-103495340-A Method of removing SOx in gas by compound alkanolamine solution BEIJING BOYUAN HENGSHENG HIGH TECHNOLOGY CO LTD 2014-01-08 CN claimed
WO-2018100137-A1 NUCLEOSIDE TRIPHOSPHATE AND NUCLEOSIDE TRIPHOSPHATE ANALOGUE PRODRUGS UNIVERSITÄT HAMBURG (DE) 2018-06-07 WO disclosed
CN-103495340-B The method of SOx in compound alcamines solution removal gas BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO.,LTD. (CN) 2015-11-18 CN disclosed
US-9045423-B2 Prophylactic and/or therapeutic agent for anemia comprising tetrahydroquinoline compound as active ingredient KOWA COMPANY, LTD. (JP) 2015-06-02 US disclosed
US-20140249144-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT KOWA COMPANY, LTD. (JP) 2014-09-04 US disclosed
US-8791090-B2 Prophylactic and/or therapeutic agent for anemia comprising tetrahydroquinoline compound as active ingredient KOWA COMPANY, LTD. (JP) 2014-07-29 US disclosed
CN-103495340-A Method of removing SOx in gas by compound alkanolamine solution BEIJING BOYUAN HENGSHENG HIGH TECHNOLOGY CO LTD 2014-01-08 CN disclosed
EP-2415764-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT Kowa Company, Ltd. (JP) 2012-02-08 EP disclosed
US-20120004197-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT KOWA COMPANY, LTD. (JP) 2012-01-05 US disclosed
US-20030032774-A1 Novel opioid peptides for the treatment of pain ASTRAZENECA AB 2003-02-13 US disclosed
CN-1161962-A Sulphonic-acid-amide derivative KONO PHARMACEUTICAL IND K K (JP) 1997-10-15 CN disclosed
US-4124579-A FOR POLYMERIC MATERIALS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249144-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT EPOR, HBG1, HBG2 KMT2A 1459/4885LMNA 4334/4885ALDH1A1 1491/4885
US-20030032774-A1 Novel opioid peptides for the treatment of pain OPRL1, OPRK1, OPRM1 KMT2A 3723/4885LMNA 4361/4885ALDH1A1 4281/4885
US-20120004197-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT EPOR, HBG1, HBG2 KMT2A 1459/4885LMNA 4334/4885ALDH1A1 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.