SCHEMBL299704

SCHEMBL299704

CCCCCCCCCCCCCCCCCC(=O)Oc1ccc(N)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MAPT P10636 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CA2 P00918 3/20 0.49
LMNA P02545 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
CYP2C19 P33261 1/20 0.49
PDE4D Q08499 1/20 0.49
HTT P42858 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MEN1 O00255 1/20 0.48
SLC22A2 O15244 1/20 0.48
TMPRSS2 O15393 1/20 0.48
F2 P00734 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16586533 1.00 KMT2A (0.59) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL27709110 1.00 KMT2A (0.59) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL11650732 1.00 KMT2A (0.59) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL11513733 0.98 KMT2A (0.57) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL224788 0.93 KMT2A (0.52) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL38661498 0.91 KMT2A (0.68) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL5696715 0.91 KMT2A (0.68) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL5696854 0.91 KMT2A (0.68) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL15549028 0.91 KMT2A (0.68) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL22914565 0.91 KMT2A (0.52) KMT2ASMN1; SMN2MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10759780-B2 Hindered amines 3V SIGMA S.P.A. (IT) 2020-09-01 US disclosed
US-20200239629-A1 HINDERED POLYMERIC AMINES 3V SIGMA S.P.A. (IT) 2020-07-30 US disclosed
EP-3424977-B1 HINDERED POLYMERIC AMINES 3V SIGMA SPA (IT) 2020-03-18 EP disclosed
EP-3428156-B1 HINDERED AMINES 3V SIGMA SPA (IT) 2020-02-12 EP disclosed
US-20190016702-A1 HINDERED AMINES 3V SIGMA S.P.A. (IT) 2019-01-17 US disclosed
EP-3428156-A1 HINDERED AMINES 3V SIGMA S.p.A (IT) 2019-01-16 EP disclosed
EP-3424977-A1 HINDERED POLYMERIC AMINES 3V SIGMA S.p.A (IT) 2019-01-09 EP disclosed
US-20190002631-A1 HINDERED POLYMERIC AMINES 3V SIGMA S.P.A. (IT) 2019-01-03 US disclosed
US-9725578-B2 Sterically hindered polymeric amines and their use as polymer stabilizers 3V SIGMA S.P.A. (IT) 2017-08-08 US disclosed
US-20170002178-A1 STABILIZER MIXTURE BASF SE (DE) 2017-01-05 US disclosed
US-4863621-A WEAR RESISTANCE, EXTREME PRESSURE LUBRICANTS CIBA-GEIGY CORPORATION (US) 1989-09-05 US disclosed
EP-0317508-A2 Aminic orthoester stabilized compositions CIBA-GEIGY AG (CH) 1989-05-24 EP disclosed
EP-0314623-A2 Substituted hydroxylamine ester stabilizers CIBA-GEIGY AG (CH) 1989-05-03 EP disclosed
EP-0313517-A2 Aliphatic esters of 1,3,2-oxazaphospholidines CIBA-GEIGY AG (CH) 1989-04-26 EP disclosed
US-4803234-A Piperidine compounds and their use as anti-oxidative, light or thermal induced degradation agents CIBA-GEIGY CORPORATION (US) 1989-02-07 US disclosed
EP-0299925-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1989-01-18 EP disclosed
EP-0292437-A2 Piperidylaminotriazine derivatives and their use as stabilizers CIBA-GEIGY AG (CH) 1988-11-23 EP disclosed
EP-0290388-A2 Polyethylene stabilizer compositions comprising compounds with piperidine groups and metal compounds CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
EP-0290393-A2 Piperidine compounds for use as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
US-4517283-A STABILIZED BY POLYALKYLPIPERIDINE COMPOUND AND PHENOL ANTIOXIDANT CIBA-GEIGY AG (CH) 1985-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200239629-A1 HINDERED POLYMERIC AMINES PARG, PARN, PUF60 KMT2A 1383/4885SMN1; SMN2 3625/4885MAPT 562/4885
US-20190016702-A1 HINDERED AMINES PARG, TAAR5, PARN KMT2A 998/4885SMN1; SMN2 4076/4885MAPT 968/4885
US-20170002178-A1 STABILIZER MIXTURE MRPL21, C9, C1R KMT2A 2354/4885SMN1; SMN2 877/4885MAPT 2188/4885
US-10759780-B2 Hindered amines PARG, TAAR5, PARN KMT2A 998/4885SMN1; SMN2 4076/4885MAPT 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.