Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360737 | 0.77 | HPGD (0.49) | HTTHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12844151 | 0.73 | HTT (0.44) | HTTHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1360946 | 0.73 | HTT (0.44) | HTTHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1840771 | 0.73 | HTT (0.44) | HTTHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12775771 | 0.70 | HTT (0.42) | HTTHPGDKMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL22468806 | 0.69 | HPGD (0.50) | HTTHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27446147 | 0.68 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL1360243 | 0.68 | — | — | |
| SCHEMBL2001301 | 0.67 | P2RX7 (0.42) | HPGDSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL1719142 | 0.67 | HPGD (0.48) | HTTHPGDKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198567-A1 | QUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | Epizyme, Inc. (US) | 2020-10-01 | — | — | WO | disclosed |