SCHEMBL27446147

SCHEMBL27446147

CCc1cnn2c(C)c(CN(C)CC)ccc12

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22480397 0.68 HTT (0.40) CHRNB2CHRNA4
SCHEMBL23109051 0.66 DRD2 (0.50)
SCHEMBL19430301 0.63 DRD2 (0.35)
SCHEMBL26485744 0.62 CYP2D6 (0.45) CHRNB2CHRNA4
SCHEMBL12548100 0.62 CHRNB2 (0.52) CHRNB2CHRNA4
SCHEMBL2001301 0.61 P2RX7 (0.42)
SCHEMBL26779173 0.61 HRH3 (0.36) CHRNB2CHRNA4
SCHEMBL23425908 0.59 EPHB3 (0.42)
SCHEMBL25644507 0.58 PYCR1 (0.64) CHRNB2CHRNA4
SCHEMBL12124982 0.57 MAPT (0.53) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024119122-A1 CDK INHIBITORS AND METHODS AND USE THEREOF RELAY THERAPEUTICS, INC. (US) 2024-06-06 WO disclosed