Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23899582 | 0.82 | KMT2A (0.42) | ELANEHPGDNPC1RAB9AMEN1 | |
| SCHEMBL22314998 | 0.82 | KMT2A (0.40) | ELANEHPGDRAB9AMEN1KMT2A | |
| SCHEMBL27312244 | 0.81 | CYP4F2 (0.44) | ELANEHPGDNPC1RAB9AMEN1 | |
| SCHEMBL21653412 | 0.81 | MBOAT4 (0.37) | ELANEHPGDNPC1RAB9AMEN1 | |
| SCHEMBL22812898 | 0.79 | ALDH1A1 (0.52) | ELANEKMT2AL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL18646461 | 0.79 | KMT2A (0.38) | ELANEHPGDNPC1RAB9AMEN1 | |
| SCHEMBL26740077 | 0.79 | HPGD (0.36) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20801346 | 0.78 | ALDH1A1 (0.43) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26741305 | 0.77 | ELANE (0.42) | ELANEHPGDNPC1RAB9AMEN1 | |
| SCHEMBL21153420 | 0.77 | KMT2A (0.42) | ELANEHPGDNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10940178-B2 | Weekly dosing regimens for anti-CD30 vc-PAB-MMAE antibody drug-conjugates | SEAGEN INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200306336-A1 | WEEKLY DOSING REGIMENS FOR ANTI-CD30 VC-PAB-MMAE ANTIBODY DRUG-CONJUGATES | SEATTLE GENETICS, INC. (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10940178-B2 | Weekly dosing regimens for anti-CD30 vc-PAB-MMAE antibody drug-conjugates | CD44, PABPC1, CD47 | ELANE 3843/4885HPGD 4819/4885NPC1 3498/4885 |
| US-20200306336-A1 | WEEKLY DOSING REGIMENS FOR ANTI-CD30 VC-PAB-MMAE ANTIBODY DRUG-CONJUGATES | CD44, PABPC1, CD47 | ELANE 3843/4885HPGD 4819/4885NPC1 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.