Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24334700 | 0.85 | GLS (0.48) | GLS | |
| SCHEMBL23011807 | 0.81 | GLS (0.49) | GLS | |
| SCHEMBL17601989 | 0.78 | MAPK1 (0.44) | — | |
| SCHEMBL19450894 | 0.78 | GLS (0.45) | GLS | |
| SCHEMBL17625567 | 0.76 | MAPK1 (0.39) | — | |
| SCHEMBL15223683 | 0.74 | GLS (0.47) | GLS | |
| SCHEMBL15223713 | 0.74 | GLS (0.46) | GLS | |
| SCHEMBL15223681 | 0.74 | GLS (0.46) | GLS | |
| SCHEMBL21907950 | 0.74 | GLS (0.45) | GLS | |
| SCHEMBL15223703 | 0.73 | GLS (0.43) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198583-A1 | BICYCLIC JAK INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2020-10-01 | — | — | WO | disclosed |