SCHEMBL22483183

SCHEMBL22483183

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc5c6c7ccccc7ccc6n(-c6ccccc6)c5c4)n3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.38
ATM Q13315 2/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 3/20 0.35
HSP90AA1 P07900 1/20 0.35
NPC1 O15118 2/20 0.35
LMNA P02545 2/20 0.35
RAB9A P51151 2/20 0.35
RECQL P46063 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HPGD P15428 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
PTGES O14684 1/20 0.33
PRMT5 O14744 1/20 0.33
MAT2A P31153 1/20 0.33
CYP1A1 P04798 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16785791 0.99 ATM (0.37) AVPR1AATMKDM4EL3MBTL1MEN1
SCHEMBL21127995 0.97 AVPR1A (0.38) AVPR1AATMKDM4EL3MBTL1MEN1
SCHEMBL24157140 0.96 MEN1 (0.37) AVPR1AATMKDM4EL3MBTL1MEN1
SCHEMBL26047936 0.95 AVPR1A (0.35) AVPR1AATMKDM4EL3MBTL1MEN1
SCHEMBL24152495 0.95 KDM4E (0.42) AVPR1AATMKDM4EL3MBTL1MEN1
SCHEMBL21863077 0.95 AVPR1A (0.35) AVPR1AATMKDM4EL3MBTL1MEN1
SCHEMBL15860077 0.95 AVPR1A (0.35) AVPR1AATMKDM4EL3MBTL1MEN1
SCHEMBL24152650 0.94 KDM4E (0.43) AVPR1AATMKDM4EL3MBTL1KMT2A
SCHEMBL22479854 0.94 GAA (0.34) AVPR1AMEN1KMT2AMAPTNPC1
SCHEMBL24361384 0.93 MEN1 (0.36) AVPR1AKDM4EMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
US-20230209856-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209856-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, LEF1 AVPR1A 3268/4885ATM 2804/4885KDM4E 2520/4885
US-11760769-B2 Composition and organic light-emitting device including the same CRY1, CRY2, LEF1 AVPR1A 3268/4885ATM 2804/4885KDM4E 2520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.