Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824610 | 0.82 | KDM4E (0.78) | TRPV1KDM4EGSK3BMEN1KMT2A | |
| SCHEMBL2249492 | 0.79 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL5658571 | 0.78 | TRPV1 (0.77) | TRPV1 | |
| SCHEMBL2243761 | 0.77 | TRPV1 (0.50) | TRPV1KDM4EMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10348739 | 0.73 | EPHX1 (0.71) | TRPV1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29971510 | 0.73 | KDM4E (1.00) | TRPV1KDM4EGSK3BMEN1KMT2A | |
| SCHEMBL1395176 | 0.73 | KDM4E (1.00) | TRPV1KDM4EGSK3BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10348748 | 0.71 | TRPV1 (0.68) | TRPV1KDM4EMEN1KMT2AMAPT | |
| Bromide SCHEMBL10348696 | 0.71 | TRPV1 (0.68) | TRPV1KDM4EMEN1KMT2AMAPT | |
| Iodide SCHEMBL10348458 | 0.71 | TRPV1 (0.68) | TRPV1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891004-B1 | PENTAFLUOROSULPHANYL-SUBSTITUTED COMPOUND AND ITS USE FOR PRODUCING MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2009-12-02 | — | — | EP | claimed |
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | GRUENENTHAL GMGH (DE) | 2009-05-28 | — | — | US | claimed |
| US-7994167-B2 | Pentafluorosulphanyl-substituted compound and its use for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | GRUENENTHAL GMGH (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | FIBP, PFAS, FPR3 | TRPV1 445/4885KDM4E 3581/4885GSK3B 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.