SCHEMBL22484768

SCHEMBL22484768

O=CNc1ccc(N2CCCN(C3CC3)CC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 5/20 0.50
L3MBTL1 Q9Y468 5/20 0.50
HRH3 Q9Y5N1 2/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MBTD1 Q05BQ5 2/20 0.43
TP53BP1 Q12888 1/20 0.42
L3MBTL4 Q8NA19 1/20 0.42
GRIN2B Q13224 1/20 0.40
WEE1 P30291 1/20 0.39
DRD2 P14416 1/20 0.39
DRD3 P35462 1/20 0.39
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22484601 0.94 L3MBTL3 (0.47) L3MBTL3L3MBTL1HRH3MEN1KMT2A
SCHEMBL14418337 0.90 HRH3 (0.48) L3MBTL3L3MBTL1HRH3MEN1KMT2A
SCHEMBL22484604 0.88 L3MBTL3 (0.67) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL13973363 0.87 L3MBTL3 (0.65) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL29037744 0.84 ALDH1A1 (0.46) L3MBTL3L3MBTL1HRH3MEN1KMT2A
SCHEMBL29037799 0.82 L3MBTL3 (0.49) L3MBTL3L3MBTL1HRH3KMT2AMBTD1
SCHEMBL10133331 0.81 TRIM24 (0.57) L3MBTL1MEN1KMT2ATRIM24TRIM33
SCHEMBL29037728 0.80 L3MBTL3 (0.50) L3MBTL3L3MBTL1HRH3MBTD1TP53BP1
SCHEMBL2320267 0.80 ALDH1A1 (0.58) L3MBTL1MEN1KMT2ATRIM24TRIM33
SCHEMBL5743788 0.77 L3MBTL3 (0.49) L3MBTL3L3MBTL1HRH3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020198368-A1 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING NEUROPORE THERAPIES, INC. (US) 2020-10-01 WO disclosed