Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | WEE1 | P30291 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22484768 | 0.94 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1KMT2AMEN1HRH3 | |
| SCHEMBL14418337 | 0.92 | HRH3 (0.48) | L3MBTL3L3MBTL1KMT2AMEN1HRH3 | |
| SCHEMBL29037744 | 0.90 | ALDH1A1 (0.46) | L3MBTL3L3MBTL1KMT2AMEN1HRH3 | |
| SCHEMBL22484604 | 0.88 | L3MBTL3 (0.67) | L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL29037799 | 0.87 | L3MBTL3 (0.49) | L3MBTL3L3MBTL1KMT2AHRH3MBTD1 | |
| SCHEMBL13973363 | 0.86 | L3MBTL3 (0.65) | L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL29037728 | 0.85 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1HRH3GAAMBTD1 | |
| SCHEMBL13973359 | 0.80 | ALDH1A1 (0.57) | KMT2AMEN1GAA | |
| SCHEMBL10133331 | 0.79 | TRIM24 (0.57) | L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL31003565 | 0.79 | HPGDS (0.43) | KMT2AMEN1GAAWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198368-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2020-10-01 | — | — | WO | disclosed |