SCHEMBL22490850

SCHEMBL22490850

CO[C@H]1[C@H](O)[C@@H](CO)O[C@H](O)[C@@H]1OCc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.46
LGALS8 O00214 2/20 0.45
SLC5A2 P31639 3/20 0.42
SLC5A1 P13866 1/20 0.42
LTA4H P09960 1/20 0.41
EPHX2 P34913 1/20 0.41
OGA O60502 1/20 0.41
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
PTGS1 P23219 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTGS2 P35354 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HIF1A Q16665 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
LGALS3 P17931 2/20 0.40
SSTR5 P35346 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21219194 0.87 SLC6A2 (0.52) SLC6A2LGALS8SLC5A2OGACYP2C19
SCHEMBL16099955 0.87 SLC6A2 (0.52) SLC6A2LGALS8SLC5A2OGACYP2C19
SCHEMBL8755194 0.84 SLC6A2 (0.46) SLC6A2LGALS8CYP2C19LGALS3SSTR5
SCHEMBL23488458 0.84 SLC6A2 (0.51) SLC6A2LGALS8SLC5A2SLC5A1OGA
SCHEMBL23488469 0.84 SLC6A2 (0.51) SLC6A2LGALS8SLC5A2SLC5A1OGA
SCHEMBL22490926 0.84 LGALS3 (0.50) LGALS8HIF1ALGALS3MAOBPARP10
SCHEMBL22490919 0.84 LGALS3 (0.50) LGALS8HIF1ALGALS3MAOBPARP10
SCHEMBL22490855 0.84 LGALS3 (0.50) LGALS8HIF1ALGALS3MAOBPARP10
SCHEMBL10708838 0.84 SLC6A2 (0.56) SLC6A2LGALS8SLC5A2CYP2C19LGALS3
SCHEMBL20741969 0.84 SLC6A2 (0.56) SLC6A2LGALS8SLC5A2CYP2C19LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed
EP-3717463-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2020-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 SLC6A2 1655/4885LGALS8 61/4885SLC5A2 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.