SCHEMBL22490926

SCHEMBL22490926

CO[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1OC(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 5/20 0.50
LGALS9 O00182 4/20 0.50
LGALS1 P09382 4/20 0.50
LGALS7; LGALS7B P47929 3/20 0.50
LGALS8 O00214 4/20 0.48
MAOB P27338 1/20 0.45
PARP10 Q53GL7 1/20 0.45
LGALS4 P56470 1/20 0.44
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
SRD5A2 P31213 1/20 0.42
HIF1A Q16665 1/20 0.41
PLA2G4B P0C869 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA5 P30532 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22490919 1.00 LGALS3 (0.50) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL22490855 1.00 LGALS3 (0.50) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488513 0.88 LGALS8 (0.64) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488143 0.86 LGALS8 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488417 0.86 LGALS8 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488412 0.86 LGALS8 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488690 0.85 LGALS3 (0.55) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL22490850 0.84 SLC6A2 (0.46) LGALS3LGALS8MAOBPARP10HIF1A
SCHEMBL23488416 0.83 LGALS9 (0.49) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488419 0.82 LGALS8 (0.49) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed
EP-3717463-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2020-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS3 156/4885LGALS9 106/4885LGALS1 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.