SCHEMBL22490895

SCHEMBL22490895

Cc1cc(C)c(C)c(C(=O)CC(=O)c2c(C)c(C)cc(C)c2C)c1C

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
FABP4 P15090 1/20 0.36
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
LMNA P02545 2/20 0.35
FKBP4 Q02790 1/20 0.35
FKBP5 Q13451 1/20 0.35
ALDH1A1 P00352 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.33
FASN P49327 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720603 0.83 KMT2A (0.50) MEN1KMT2APGK1PGK2FKBP4
SCHEMBL11360578 0.81 GSK3B (0.42) KMT2ALMNAALDH1A1NPC1RAB9A
SCHEMBL11364813 0.81 GSK3B (0.43) PGK1PGK2FASN
SCHEMBL14435878 0.78 KMT2A (0.34) MEN1KMT2ANPC1RAB9AKDM4E
SCHEMBL26096892 0.78 PLA2G2A (0.32) MEN1KMT2APGK1PGK2FASN
SCHEMBL9352415 0.78 KMT2A (0.50) MEN1KMT2AFABP4LMNAALDH1A1
SCHEMBL5996573 0.78 FASN (0.37) MEN1KMT2AFABP4PGK1PGK2
SCHEMBL11053483 0.75 MEN1 (0.51) MEN1KMT2ALMNAALDH1A1RAB9A
SCHEMBL1259455 0.74 LDHA (0.34) FABP4PGK1PGK2LMNAALDH1A1
SCHEMBL3735175 0.74 CYP3A4 (0.47) MEN1KMT2ALMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230137820-A1 PHOSPHORESCENT aNHC-BASED PLATINUM (II) COMPLEXES Technische Universität Dresden (DE) 2023-05-04 US disclosed
EP-3717495-A1 PHOSPHORESCENT PLATINUM (II) ANHC COMPLEXES Technische Universität Dresden (DE) 2020-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230137820-A1 PHOSPHORESCENT aNHC-BASED PLATINUM (II) COMPLEXES NDC1, ORC3, NUDC MEN1 1752/4885KMT2A 2343/4885FABP4 1444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.