SCHEMBL5996573

SCHEMBL5996573

Cc1cc(C)c(C)c(C(=O)CCP)c1C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FASN P49327 2/20 0.37
FABP4 P15090 1/20 0.36
PLA2G2A P14555 2/20 0.35
PLA2G5 P39877 2/20 0.35
NPSR1 Q6W5P4 1/20 0.32
SLC5A1 P13866 1/20 0.32
SLC5A2 P31639 1/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
FFAR1 O14842 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5993510 0.88 FASN (0.35) FASNFABP4PLA2G2APLA2G5NPSR1
SCHEMBL5996181 0.82 PLA2G2A (0.35) FASNFABP4PLA2G2APLA2G5GFER
SCHEMBL5995789 0.82 MEN1 (0.33) FASNPLA2G2APLA2G5SLC5A1SLC5A2
SCHEMBL9352415 0.79 KMT2A (0.50) FABP4NPSR1FFAR1MEN1KMT2A
SCHEMBL5997078 0.79 ALDH1A1 (0.44) FABP4NPSR1MEN1KMT2A
SCHEMBL22490895 0.78 MEN1 (0.37) FASNFABP4PGK1PGK2MEN1
SCHEMBL5997143 0.77 ALDH1A1 (0.40) FASNSLC5A1SLC5A2MEN1KMT2A
SCHEMBL5995744 0.77 FASN (0.33) FASNPLA2G2APLA2G5FFAR1MEN1
SCHEMBL28753836 0.76 PLA2G2A (0.41) FASNFABP4PLA2G2APLA2G5FFAR1
SCHEMBL9720603 0.76 KMT2A (0.50) FASNPLA2G2APLA2G5PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109250-B2 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. (US) 2006-09-19 US disclosed
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-20050004247-A1 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. 2005-01-06 US disclosed
EP-1446410-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES Ciba SC Holding AG (CH) 2004-08-18 EP disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
WO-2003044030-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 FASN 1351/4885FABP4 3705/4885PLA2G2A 2876/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 FASN 2990/4885FABP4 3862/4885PLA2G2A 1260/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 FASN 2546/4885FABP4 3747/4885PLA2G2A 2925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.