SCHEMBL22490904

SCHEMBL22490904

O=C(c1ccccc1)[C@@]1(O)C(O)O[C@@H](CO)[C@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 2/20 0.44
LGALS1 P09382 2/20 0.44
LGALS3 P17931 2/20 0.44
LGALS7; LGALS7B P47929 2/20 0.44
HK1 P19367 2/20 0.41
HK2 P52789 2/20 0.41
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26693098 0.79 LGALS9 (0.40) LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1
SCHEMBL9655087 0.79 CA12 (0.34) LGALS9LGALS1LGALS3
SCHEMBL28854038 0.78 TNF (0.42) LGALS9LGALS1LGALS3LGALS7; LGALS7BALDH1A1
SCHEMBL28448346 0.78 HK1 (0.41) LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1
SCHEMBL28448343 0.78 HK1 (0.41) LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1
SCHEMBL29602084 0.77 LGALS9 (0.33) LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1
SCHEMBL30843273 0.76 LGALS9 (0.40) LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1
SCHEMBL29131407 0.73 SLC5A2 (0.42)
SCHEMBL9500829 0.73 SLC5A2 (0.42)
SCHEMBL9443607 0.72 LGALS8 (0.44) LGALS9LGALS1LGALS3LGALS7; LGALS7BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed
EP-3717463-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2020-10-07 EP disclosed
CN-111433193-A Novel conjugates of agents and moieties capable of binding to glucose sensing proteins 赛诺菲 2020-07-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS9 106/4885LGALS1 50/4885LGALS3 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.