Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16534543 | 1.00 | ADRA2A (0.45) | ADRA2AADRA1DADRA1AADRA1BHSD17B10 | |
| SCHEMBL30436522 | 1.00 | ADRA2A (0.45) | ADRA2AADRA1DADRA1AADRA1BHSD17B10 | |
| Toluene SCHEMBL22466777 | 0.94 | ALDH1A1 (0.42) | ADRA2AADRA1DADRA1AADRA1BHSD17B10 | |
| SCHEMBL16534708 | 0.86 | FFAR1 (0.43) | HSD17B10TDP1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL16534290 | 0.86 | ALDH1A1 (0.43) | ADRA2AADRA1DADRA1AADRA1BHSD17B10 | |
| SCHEMBL16534664 | 0.85 | TDP1 (0.41) | ADRA1AHSD17B10TDP1MEN1KMT2A | |
| SCHEMBL16534907 | 0.84 | SIGMAR1 (0.39) | TDP1MEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL20480080 | 0.83 | ADRA2A (0.49) | ADRA2AADRA1DADRA1AADRA1BHSD17B10 | |
| SCHEMBL20482712 | 0.83 | ADRA2A (0.49) | ADRA2AADRA1DADRA1AADRA1BHSD17B10 | |
| SCHEMBL30436776 | 0.83 | ADRA2A (0.49) | ADRA2AADRA1DADRA1AADRA1BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717476-A1 | PROCESS FOR THE PREPARATION OF 2-(5-METHOXYISOCHROMAN-1 -YL)-4,5-DIHYDRO-1 H-IMIDAZOLE AND THE HYDROGENSULFATE SALT THEREOF | Orion Corporation (FI) | 2020-10-07 | — | — | EP | claimed |
| EP-3717476-A1 | PROCESS FOR THE PREPARATION OF 2-(5-METHOXYISOCHROMAN-1 -YL)-4,5-DIHYDRO-1 H-IMIDAZOLE AND THE HYDROGENSULFATE SALT THEREOF | Orion Corporation (FI) | 2020-10-07 | — | — | EP | disclosed |