Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828590 | 1.00 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19TRPA1KDM4E | |
| SCHEMBL3779619 | 0.82 | TRPA1 (0.48) | CYP1A2CYP2C9CYP2C19TRPA1KDM4E | |
| SCHEMBL9464129 | 0.79 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19TRPA1KDM4E | |
| SCHEMBL11557519 | 0.77 | CSNK1E (0.46) | TRPA1SIGMAR1 | |
| SCHEMBL27571377 | 0.76 | TRPA1 (0.45) | CYP1A2TRPA1KDM4ELMNAMAPK1 | |
| SCHEMBL27440222 | 0.76 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19TRPA1LMNA | |
| SCHEMBL27440219 | 0.76 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19TRPA1LMNA | |
| SCHEMBL9618402 | 0.76 | CSNK1E (0.48) | TRPA1 | |
| SCHEMBL10599737 | 0.76 | CSNK1E (0.51) | CYP1A2TRPA1KDM4ELMNAPOLB | |
| SCHEMBL22173701 | 0.74 | HIF1A (0.41) | CYP1A2CYP2C9CYP2C19TRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448204-B | Vaccine against klebsiella pneumoniae | 爱杜西亚药品有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-11891413-B2 | Vaccine against Klebsiella pneumoniae | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-02-06 | — | — | US | disclosed |
| US-20210386845-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-16 | — | — | US | disclosed |
| EP-3717498-A1 | VACCINE AGAINSTKLEBSIELLA PNEUMONIAE | Vaxxilon AG (CH) | 2020-10-07 | — | — | EP | disclosed |
| CN-111448204-A | Vaccine against klebsiella pneumoniae | 瓦希隆股份公司 | 2020-07-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891413-B2 | Vaccine against Klebsiella pneumoniae | UBXN1, MLX, UBXN4 | CYP1A2 4533/4885CYP2C9 4614/4885CYP2C19 4779/4885 |
| US-20210386845-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | UBXN1, MLX, UBXN4 | CYP1A2 4533/4885CYP2C9 4614/4885CYP2C19 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.