Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440219 | 0.81 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL27440222 | 0.81 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL16265936 | 0.80 | TRPA1 (0.50) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL3779619 | 0.79 | TRPA1 (0.48) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL22491793 | 0.79 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL828590 | 0.79 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL29387097 | 0.77 | TRPA1 (0.43) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL27674334 | 0.77 | TRPA1 (0.43) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL11022533 | 0.76 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19TRPA1FDPS | |
| SCHEMBL4445459 | 0.74 | TRPA1 (0.52) | CYP1A2CYP2C9CYP2C19TRPA1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290531-B2 | Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections | Universitätsklinikum Freiburg (DE) | 2016-03-22 | — | — | US | disclosed |
| EP-2500349-B1 | Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections | Universitätsklinikum Freiburg (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20140050741-A1 | SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PROPHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS | UNIVERSITEIT LEIDEN (NL) | 2014-02-20 | — | — | US | disclosed |
| EP-2500349-A1 | Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections | Universitätsklinikum Freiburg (DE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2012119846-A1 | SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PRO-PHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS | Universitätsklinikum Freiburg (DE) | 2012-09-13 | — | — | WO | disclosed |
| CN-101501003-A | Phenyl-pyrazole derivatives as non-steroidal glucocorticoid receptor ligands | GLAXO GROUP LTD (GB) | 2009-08-05 | — | — | CN | disclosed |
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140050741-A1 | SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PROPHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS | LTA, LTN1, LTC4S | CYP1A2 4597/4885CYP2C9 4812/4885CYP2C19 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.