SCHEMBL2249225

SCHEMBL2249225

COc1ccc2c(Br)c3cc(OC)ccc3c(Br)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.50
▸ KDM4E B2RXH2 8/20 0.50
▸ MAPT P10636 5/20 0.50
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ HSD17B10 Q99714 3/20 0.50
▸ TSHR P16473 1/20 0.50
▸ GFER P55789 1/20 0.50
▸ CA1 P00915 4/20 0.46
▸ CA2 P00918 4/20 0.46
▸ CA7 P43166 4/20 0.46
▸ CA9 Q16790 4/20 0.46
▸ CA12 O43570 2/20 0.46
▸ CA14 Q9ULX7 2/20 0.46
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ GPR84 Q9NQS5 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ STAT1 P42224 1/20 0.44
▸ HPGD P15428 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17133046 0.79 ALDH1A1 (0.58) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL17133042 0.79 ALDH1A1 (0.58) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL12575152 0.79 KDM4E (0.48) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL4013733 0.78 ABL1 (0.49) ALDH1A1KDM4EMAPTHSD17B10TSHR
SCHEMBL1470268 0.74 NPSR1 (0.41) ALDH1A1KDM4EHSD17B10GFERPOLB
SCHEMBL1470937 0.74 PARP15 (0.52) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL16740905 0.74 PDE3B (0.64) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL4789564 0.73 CYP1A2 (0.56) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL1615040 0.73 MAPT (0.59) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL17536913 0.73 MAPT (0.59) ALDH1A1KDM4EMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101918512-B Green luminescent materials E I DU PONT DENEMOURS AND COMPANY 2014-09-24 — — CN disclosed
EP-2197981-B1 GREEN LUMINESCENT MATERIALS DU PONT (US) 2013-04-03 — — EP disclosed
US-8273468-B2 Green luminescent materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-09-25 — — US disclosed
US-8273468-B2 Green luminescent materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-09-25 — — US disclosed
US-8273468-B2 Green luminescent materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-09-25 — — US disclosed
US-20110186836-A1 GREEN LUMINESCENT MATERIALS E.I.DU PONT DE NEMOURS AND COMPANY (US) 2011-08-04 — — US disclosed
US-20110186836-A1 GREEN LUMINESCENT MATERIALS E.I.DU PONT DE NEMOURS AND COMPANY (US) 2011-08-04 — — US disclosed
US-20110186836-A1 GREEN LUMINESCENT MATERIALS E.I.DU PONT DE NEMOURS AND COMPANY (US) 2011-08-04 — — US disclosed
EP-2197981-A2 GREEN LUMINESCENT MATERIALS E. I. Du Pont de Nemours and Company (US) 2010-06-23 — — EP disclosed
US-20080303429-A1 GREEN LUMINESCENT MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2008-12-11 — — US disclosed
WO-2008150828-A2 GREEN LUMINESCENT MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-11 — — WO disclosed
US-20080303429-A1 GREEN LUMINESCENT MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2008-12-11 — — US disclosed
WO-2008150828-A2 GREEN LUMINESCENT MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-11 — — WO disclosed
US-20080303429-A1 GREEN LUMINESCENT MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2008-12-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110186836-A1 GREEN LUMINESCENT MATERIALS IK, GLB1, AFF2 ALDH1A1 905/4885KDM4E 2213/4885MAPT 2628/4885
US-20080303429-A1 GREEN LUMINESCENT MATERIALS IK, GLB1, AFF2 ALDH1A1 905/4885KDM4E 2213/4885MAPT 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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