SCHEMBL1615040

SCHEMBL1615040

COc1ccc2c3ccccc3c3ccc(OC)cc3c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.59
KDM4E B2RXH2 7/20 0.59
ALDH1A1 P00352 7/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
HSD17B10 Q99714 3/20 0.59
HPGD P15428 2/20 0.59
L3MBTL1 Q9Y468 3/20 0.57
HTT P42858 2/20 0.57
LMNA P02545 4/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2A6 P11509 1/20 0.56
TSHR P16473 1/20 0.52
GFER P55789 1/20 0.52
NPC1 O15118 4/20 0.52
RAB9A P51151 4/20 0.52
MAOA P21397 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
ABCG2 Q9UNQ0 1/20 0.52
POLB P06746 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3456619 1.00 MAPT (0.59) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL17536913 1.00 MAPT (0.59) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL2021618 1.00 MAPT (0.59) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL13070418 0.93 MAPT (0.53) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL18133359 0.93 CYP1A2 (0.61) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL17133046 0.92 ALDH1A1 (0.58) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL17133042 0.92 ALDH1A1 (0.58) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL16108132 0.91 MAPT (0.52) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL10023273 0.89 ACHE (0.52) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL17552365 0.89 ACHE (0.52) MAPTKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12082493-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-09-03 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-10957858-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-23 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
EP-2200956-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-06-30 EP disclosed
EP-2185532-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP Universal Display Corporation (US) 2010-05-19 EP disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 WO disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 WO disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12082493-B2 Organic electroluminescent materials and devices NONO, ORC3, TYR MAPT 3312/4885KDM4E 3409/4885ALDH1A1 668/4885
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, TYR MAPT 3312/4885KDM4E 3409/4885ALDH1A1 668/4885
US-10957858-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 MAPT 3291/4885KDM4E 3642/4885ALDH1A1 320/4885
US-11690286-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 MAPT 3291/4885KDM4E 3642/4885ALDH1A1 320/4885
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC MAPT 1058/4885KDM4E 431/4885ALDH1A1 1684/4885
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 MAPT 3291/4885KDM4E 3642/4885ALDH1A1 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.