Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | MDH1 | P40925 | 1/20 | 0.49 |
| ▸ | MDH2 | P40926 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | LIPC | P11150 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19702689 | 1.00 | LIPE (0.50) | LIPEMDH1MDH2ADRB2ENPP2 | |
| SCHEMBL22493047 | 0.89 | EPHX2 (0.51) | EPHX2ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL19702699 | 0.89 | ALDH1A1 (0.50) | ENPP2EPHX2ALDH1A1GAAMAPT | |
| SCHEMBL19703169 | 0.89 | ALDH1A1 (0.50) | ENPP2EPHX2ALDH1A1GAAMAPT | |
| SCHEMBL19702685 | 0.88 | MAPT (0.58) | ADRB2EPHX2ALDH1A1GAAMAPT | |
| SCHEMBL19702687 | 0.86 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19702646 | 0.86 | KMT2A (0.55) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19702931 | 0.86 | KMT2A (0.55) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19702653 | 0.86 | KMT2A (0.55) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19702683 | 0.85 | POLB (0.52) | ALDH1A1GAARAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200306248-A1 | FORMULATIONS FOR SUBSTITUTED 3-PYRROLIDINES, COMPOSITIONS CONTAINING, AND USES OF, SAME | GDD THERAPEUTICS, LLC (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200306248-A1 | FORMULATIONS FOR SUBSTITUTED 3-PYRROLIDINES, COMPOSITIONS CONTAINING, AND USES OF, SAME | SLC7A1, ABCG2, SLC46A1 | LIPE 2948/4885MDH1 300/4885MDH2 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.