Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26858873 | 0.95 | ADRB1 (0.38) | CTSKADRB1LMNACYP1A2CYP2D6 | |
| SCHEMBL22481296 | 0.84 | ADRB1 (0.54) | CTSKADRB1LMNASMN1; SMN2KDM4E | |
| SCHEMBL22481314 | 0.84 | ADRB1 (0.54) | CTSKADRB1LMNASMN1; SMN2KDM4E | |
| SCHEMBL22481122 | 0.81 | ADRB1 (0.54) | CTSKADRB1LMNASMN1; SMN2KDM4E | |
| SCHEMBL22481295 | 0.81 | ADRB1 (0.54) | CTSKADRB1LMNASMN1; SMN2KDM4E | |
| SCHEMBL22493356 | 0.80 | ADRB1 (0.39) | CTSKADRB1LMNACYP1A2CYP2D6 | |
| SCHEMBL22481138 | 0.79 | ADRB1 (0.56) | CTSKADRB1LMNACYP1A2CYP2D6 | |
| SCHEMBL22481230 | 0.79 | ADRB1 (0.56) | CTSKADRB1LMNACYP1A2CYP2D6 | |
| SCHEMBL8274281 | 0.71 | CTSK (0.53) | CTSKLMNASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL22481164 | 0.70 | ADRB1 (0.55) | ADRB1LMNACYP1A2CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |