Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22481138 | 0.85 | ADRB1 (0.56) | ADRB1CTSKMALT1CYP1A2CYP2D6 | |
| SCHEMBL22481230 | 0.85 | ADRB1 (0.56) | ADRB1CTSKMALT1CYP1A2CYP2D6 | |
| SCHEMBL26858873 | 0.84 | ADRB1 (0.38) | ADRB1CTSKMALT1CYP1A2CYP2D6 | |
| SCHEMBL22481122 | 0.81 | ADRB1 (0.54) | ADRB1CTSKCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL22481296 | 0.81 | ADRB1 (0.54) | ADRB1CTSKCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL22481314 | 0.81 | ADRB1 (0.54) | ADRB1CTSKCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL22481295 | 0.81 | ADRB1 (0.54) | ADRB1CTSKCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL22493237 | 0.80 | CTSK (0.41) | ADRB1CTSKCYP1A2CYP2D6LMNA | |
| SCHEMBL22481308 | 0.75 | ADRB1 (0.54) | ADRB1CYP2D6CYP3A4LMNAHIF1A | |
| SCHEMBL22864246 | 0.74 | ADRB1 (0.44) | ADRB1CYP2D6LMNAHIF1AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |