⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835928 | 1.00 | — | — | |
| SCHEMBL19884781 | 1.00 | — | — | |
| SCHEMBL13295203 | 0.83 | — | — | |
| SCHEMBL14287970 | 0.78 | — | — | |
| Procysteine SCHEMBL14671318 | 0.76 | — | — | |
| SCHEMBL3930680 | 0.75 | GABRA5 (0.38) | — | |
| SCHEMBL9885411 | 0.75 | GABRA5 (0.38) | — | |
| SCHEMBL3998826 | 0.74 | GPR35 (0.37) | — | |
| SCHEMBL15330742 | 0.74 | — | — | |
| SCHEMBL272903 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137506-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | CURASEN THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| CN-113004217-A | 4, 5-dihydrothiazole compound containing dihydrazide and preparation and application thereof | 天津农学院 | 2021-06-22 | — | — | CN | disclosed |
| WO-2021003161-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |