Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.91 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.64 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.63 |
| ▸ | CNR1 | P21554 | 2/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15285230 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL15285227 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL20398924 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL22494088 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL22494098 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL22494109 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL22494087 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL22494108 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL22494089 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 | |
| SCHEMBL18797438 | 1.00 | FAAH (0.91) | FAAHEPHX2SLC6A5CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-21 | — | — | US | disclosed |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | PC, UQCRC1, SQOR | FAAH 1063/4885EPHX2 1255/4885SLC6A5 3986/4885 |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | PC, UQCRC1, SQOR | FAAH 1063/4885EPHX2 1255/4885SLC6A5 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.