Isoquercetin

Isoquercetin

SCHEMBL22495101

O=c1c(OC2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 6/20 1.00
KDM4E B2RXH2 5/20 1.00
AKR1B1 P15121 5/20 1.00
EPHX2 P34913 5/20 1.00
GAA P10253 4/20 1.00
POLB P06746 3/20 1.00
MAPT P10636 3/20 1.00
CA12 O43570 3/20 1.00
CA2 P00918 3/20 1.00
CA4 P22748 3/20 1.00
CA7 P43166 3/20 1.00
ALPL P05186 2/20 1.00
ALPI P09923 2/20 1.00
SLCO2B1 O94956 2/20 1.00
MAOA P21397 2/20 1.00
XDH P47989 2/20 1.00
ADRA2C P18825 1/20 1.00
NOX4 Q9NPH5 1/20 1.00
KDM1A O60341 1/20 1.00
HMGB1 P09429 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoquercetin SCHEMBL181306 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL15147267 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL2286562 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL12710506 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL6849311 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL561412 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL24609 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL19214052 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL21244358 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL672012 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113720929-A Method for distinguishing albino and etiolated variety finished tea 中国农业科学院茶叶研究所 2021-11-30 CN claimed
EP-4687934-B1 A NATURAL MATRIX MIXTURE FOR THE TREATMENT OF BONE FRAGILITY BIOS THERAPY PHYSIOLOGICAL SYSTEMS FOR HEALTH S P A (IT) 2026-03-18 EP disclosed
EP-4696314-A1 A NATURAL MATRIX MIXTURE FOR THE TREATMENT OF BONE FRAGILITY Bios-Therapy, Physiological Systems for Health S.p.A. (IT) 2026-02-18 EP disclosed
CN-119086739-A Method for measuring content of effective components in lotus leaf and preparation thereof 清华大学 2024-12-06 CN disclosed
CN-119074747-A A product for treating helicobacter pylori negative chronic atrophic gastritis with intestinal metaplasia and/or with abnormal hyperplasia and preventing gastric cancer, and its treatment method 清华大学 2024-12-06 CN disclosed
CN-113720929-A Method for distinguishing albino and etiolated variety finished tea 中国农业科学院茶叶研究所 2021-11-30 CN disclosed
US-20200315998-A1 COMPOSITION FOR IMPROVING INTESTINAL BARRIER FUNCTION SUNTORY HOLDINGS LIMITED (JP) 2020-10-08 US disclosed
CN-107073026-A Bioactive substance for treating hyperglycemic disorder is combined 百益康食品股份有限公司 2017-08-18 CN disclosed
CN-103599146-B A kind of preparation method of diuretic compositions and purposes HUAIHAI INSTITUTE OF TECHNOLOGY (CN) 2016-04-27 CN disclosed
CN-103599146-A Preparation method and use of diuretic composition HUAIHAI INST TECHNOLOGY 2014-02-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200315998-A1 COMPOSITION FOR IMPROVING INTESTINAL BARRIER FUNCTION FABP2, SLC10A2, VIP P4HB 3227/4885KDM4E 4310/4885AKR1B1 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.