Isoquercetin

Isoquercetin

SCHEMBL12710506

O=c1c(OC2OC(CO)[C@@H](O)C(O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 6/20 1.00
KDM4E B2RXH2 5/20 1.00
AKR1B1 P15121 5/20 1.00
EPHX2 P34913 5/20 1.00
GAA P10253 4/20 1.00
POLB P06746 3/20 1.00
MAPT P10636 3/20 1.00
CA12 O43570 3/20 1.00
CA2 P00918 3/20 1.00
CA4 P22748 3/20 1.00
CA7 P43166 3/20 1.00
ALPL P05186 2/20 1.00
ALPI P09923 2/20 1.00
SLCO2B1 O94956 2/20 1.00
MAOA P21397 2/20 1.00
XDH P47989 2/20 1.00
ADRA2C P18825 1/20 1.00
NOX4 Q9NPH5 1/20 1.00
KDM1A O60341 1/20 1.00
HMGB1 P09429 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoquercetin SCHEMBL181306 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL15147267 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL2286562 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL6849311 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL561412 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL24609 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL19214052 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL21244358 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL22495101 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL672012 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110078916-A1 SUPERCOOLING PROMOTING AGENT FUJIKAWA SEIZO 2011-04-07 US disclosed
US-20110078916-A1 SUPERCOOLING PROMOTING AGENT FUJIKAWA SEIZO 2011-04-07 US disclosed
US-7837895-B2 Supercooling promoting agent NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2010-11-23 US disclosed
US-7837895-B2 Supercooling promoting agent NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2010-11-23 US disclosed
US-20090302265-A1 Supercooling promoting agent OLYMPUS CORPORATION (JP) 2009-12-10 US disclosed
US-20090302265-A1 Supercooling promoting agent OLYMPUS CORPORATION (JP) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302265-A1 Supercooling promoting agent FIS1, MYB, AQP1 P4HB 3023/4885KDM4E 3228/4885AKR1B1 2757/4885
US-20110078916-A1 SUPERCOOLING PROMOTING AGENT FIS1, MYB, AQP1 P4HB 3023/4885KDM4E 3228/4885AKR1B1 2757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.